Fig. 1 | British Journal of Cancer

Fig. 1

From: Vinorelbine, cyclophosphamide and 5-FU effects on the circulating and intratumoural landscape of immune cells improve anti-PD-L1 efficacy in preclinical models of breast cancer and lymphoma

Fig. 1

Total numbers of monocytes, MDSCs, APCs and Tregs in mice treated with different types and dosages of chemotherapy drugs. BALB/c mice (n = 5 per study arm) were treated with different dosages of V, C and 5-FU and bleed weekly for 3 weeks to enumerate total numbers of circulating monocytes (top panel on the left), MDSCs (top panel on the right), APCs (bottom panel on the left) and Tregs (bottom panel on the right). MDSCs are shown as the total of monocytic-MDSCs (about 10% of all MDSCs) and granulocytic-MDSCs (about 90% of the total population)

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