Table 2 Relationship between fusion genes revealed by RNA-seq and clinicopathological characteristics in 147 patients with colorectal cancer

From: Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer

 

(No.)

Fusion genes

P value

 

Absent

Present

Age (years)

147

60.1 ± 1.00

60.7 ± 2.73

0.852

Size (cm)

147

5.81 ± 0.19

4.76 ± 0.33

0.050

Sex

   

0.819

 Male

77

68 (88.3)

9 (11.7)

 Female

70

60 (85.7)

10 (14.3)

Location

   

0.162

 Right colon

56

46 (82.1)

10 (17.9)

 Left colon

91

82 (90.1)

9 (9.9)

Histological typea

   

0.093

 Well

27

23 (85.2)

4 (14.8)

 Moderately

111

99 (89.2)

12 (10.8)

 Poorly + Mucinous

9

6 (66.7)

3 (33.3)

Invasion depthb

   

0.463

 T1

1

1 (100.0)

0 (0.0)

 T2

16

13 (81.3)

3 (18.8)

 T3

108

95 (88.0)

13 (12.0)

 T4

22

19 (86.4)

3 (13.6)

Perineural invasion

   

0.452

 Negative

89

76 (85.4)

13 (14.6)

 Positive

58

52 (89.7)

6 (10.3)

Lymphovascular emboli

   

0.553

 Negative

116

102 (87.9)

14 (12.1)

 Positive

31

26 (83.9)

5 (16.1)

Lymph node

   

.

   

0.521

 Negative

72

64 (88.9)

8 (11.1)

 Positive

75

64 (85.3)

11 (14.7)

Microsatellite status

   

0.025

 MSS+MSI−L

126

113 (89.7)

13 (10.3)

 MSI-H

21

15 (71.4)

6 (28.6)

  1. aBetween well+moderately vs. poorly+mucinous
  2. bBetween T1 + T2 vs. T3 + T4