Table 2 Response to treatment

From: Efficacy of nivolumab in pre-treated non-small-cell lung cancer patients harbouring KRAS mutations

Response, n (%)

KRAS-positive (n = 206)

KRAS-negative (n = 324)

P-value

ORR

41 (20)

55 (17)

0.39

DCR

96 (47)

134 (41)

0.23

Best overall response

  CR

2 (1)

1 (<1)

 

  PR

39 (19)

54 (17)

 

  SD

55 (27)

79 (24)

 

  PD

88 (43)

153 (47)

 

  Death

12 (5)

30 (9)

 

  Not determined

10 (5)

7 (2)

 
  1. n number of patients, ORR objective response rate, DCR disease control rate, CR complete response, PR partial response, SD stable disease, PD progression disease