Fig. 4

Waterfall plot of best response to therapy. Forty-nine patients received ≥ 2 cycles of NUC-1031 and had a scan for assessment of efficacy. Clinical activity was achieved across 19 primary cancer types, the most frequent being ovarian, pancreatic, biliary and colorectal. Eleven patients had progressive disease and the best overall responses were five PRs (10%) and 33 SDs (67%). Of the 33 SDs, 12 (24%) were of at least 6 months duration