Table 2 Treatment-related toxicities occurring in ≥10% of patients (N, %)
Dose | 195 mg/m2 | 390 mg/m2 | 450 mg/m2 | 550 mg/m2 | Total | |||||
|---|---|---|---|---|---|---|---|---|---|---|
N | 10 | 17 | 11 | 4 | 42 | |||||
Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 3–4 | Grade 1–2 | Grade 3–4 | |
Anaemia | 8 (80) | 2 (20) | 14 (82) | 3 (18) | 11 (100) | 4 (36) | 3 (75) | 1 (25) | 36 (86) | 10 (24) |
Fatigue | 2 (20) | 0 (0) | 7 (41) | 1 (6) | 6 (55) | 0 (0) | 2 (50) | 1 (25) | 17 (40) | 2 (2) |
Hypoxia | 0 (0) | 2 (20) | 1 (6) | 5 (29) | 2 (18) | 1 (9) | 0 (0) | 3 (75) | 3 (7) | 11 (26) |
Vomiting | 1 (10) | 1 (10) | 2 (12) | 1 (6) | 0 (0) | 0 (0) | 2 (50) | 0 (0) | 5 (12) | 2 (5) |
Nausea | 1 (10) | 1 (10) | 1 (6) | 0 (0) | 1 (9) | 0 (0) | 3 (75) | 0 (0) | 6 (14) | 1 (2) |
