Fig. 4 | British Journal of Cancer

Fig. 4

From: Combinations of BRAF inhibitor and anti-PD-1/PD-L1 antibody improve survival and tumour immunity in an immunocompetent model of orthotopic murine anaplastic thyroid cancer

Fig. 4

a One week of combination therapy led to a dramatic increase in F4/80+ myeloid cells. b All mice treated with PLX4720 singly or in combination had a dramatic increase in TAMs, >98% of which were M1-polarised (F4/80+CD206−IA/IE+), along with c. A dramatic decrease in monocytic MDSCs. N = 4 mice per group, repeated twice

Back to article page