Table 3 Comparison of changes in secondary outcomes after 1 month and at follow-up (7 months)

From: Manual lymphatic drainage adds no further volume reduction to Complete Decongestive Therapy on breast cancer-related lymphoedema: a multicentre, randomised, single-blind trial

 

T+MLD

T−MLD

Between-group difference

Mean

SE

Mean

SE

Mean

SE

95% CI

p Value

After 1 month

        

 Heaviness in the arm (scale, 0–10)

2.9

0.4

3.8

0.4

−0.9

0.5

−1.9; 0.1

0.089

 Tension in the arm (scale, 0–10)

2.7

0.4

3.5

0.4

−0.8

0.6

−1.9; 0.3

0.137

 Tension in the shoulder (scale 0–10)

2.1

0.4

3.5

0.4

−1.4

0.5

−2.4; −0.4

0.009

 Tension in the chest (scale, 0–10)

3.5

0.4

3.3

0.4

0.2

0.5

−0.9; 1.2

0.746

 Mobility (scale, 0–5)

1.3

0.1

1.5

0.1

−0.2

0.1

−0.5; 0.1

0.149

 Self-care (scale, 0–5)

1.4

0.1

1.6

0.1

−0.2

0.1

−0.5; 0.1

0.116

 Usual activities (scale, 0–5)

2.0

0.1

2.1

0.1

−0.1

0.2

−0.4; 0.3

0.711

 Pain (scale, 0–5)

2.0

0.1

2.1

0.1

−0.1

0.2

−0.5; 0.1

0.370

 Anxiety (scale, 0–5)

1.5

0.1

1.3

0.1

0.1

0.1

−0.1; 0.4

0.235

 Health today (VAS 0–100)

75.3

2.7

71.2

2.8

4.1

3.9

−3.6; 11.7

0.292

 BMI (kg/m2)

29.2

0.1

29.2

0.1

−0.0

0.2

−0.3; 0.3

0.972

At follow-up

  Heaviness in the arm (scale, 0–10)

3.6

0.4

3.5

0.4

0.1

0.5

−1.0; 1.1

0.923

  Tension in the arm (scale, 0–10)

3.5

0.4

3.1

0.4

0.4

0.6

−0.7; 1.4

0.512

  Tension in the shoulder (scale 0–10)

2.7

0.4

2.7

0.4

−0.1

0.5

−1.1; 1.0

0.919

  Tension in the chest (scale, 0–10)

3.6

0.4

3.1

0.4

0.5

0.5

−0.6; 1.5

0.393

  Mobility (scale, 0–5)

1.5

0.1

1.6

0.1

−0.2

0.1

−0.4; 0.1

0.285

  Self-care (scale, 0–5)

1.2

0.1

1.4

0.1

−0.2

0.1

−0.5; 0.1

0.092

  Usual activities (scale, 0–5)

2.0

0.1

2.1

0.1

−0.1

0.2

−0.4; 0.3

0.623

  Pain (scale, 0–5)

2.0

0.1

2.2

0.1

−0.2

0.2

−0.5; 0.1

0.315

  Anxiety (scale, 0–5)

1.4

0.1

1.4

0.1

−0.1

0.1

−0.2; 0.2

0.876

  Health today (VAS 0–100)

74.4

2.7

74.7

2.8

−0.3

3.9

−8.0; 7.3

0.931

  BMI (kg/m2)

29.2

0.1

29.4

0.1

−0.2

0.2

−0.5; 0.1

0.234

  1. BMI body mass index, SE standard error, 95% CI 95% confidence intervals
  2. p value from the superiority trial using a two-sided test hypothesis