Fig. 3

Metastasis-free survival according to the ICR classification within the different risk groups defined by three proliferation-based prognostic signatures in the 2131 HR+/HER2− patients. Kaplan–Meier MFS curves in patients according to the ICR1-3 and the ICR4 classes in the HR+/HER2− subtype and according to the relapse risk groups defined by the 70-gene signature (a), the Recurrence score (b), and the ROR-P score (c). d– f Similar to (a–c), respectively, but the low-risk and intermediate-risk curves are not stratified according to ICR and are pooled for (e) and (f). The p-values are indicated (log-rank test)