Fig. 2
From: Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit
Modification of immune metagene expression by trastuzumab a Correlation between MHC-II expression at baseline and its modulation by trastuzumab (fold-change) in all cases of the TRUP cohort. Spearman coefficients and relative p-values are shown. b–d Modulation of MHC-II (b), LCK (c), and HCK (d) metagene expression in post-treatment vs pretreatment biopsies according to response to trastuzumab-based chemotherapy as evaluated at surgery. Fold-change in C+K+ tumours is also shown. p-values by unpaired t-test
