Table 3 Characteristics of patients with detectable CTCs
ID | Primary site | Grade | Morphology | Ki67 (%) | Bone metastases | CTCs (n) | CXCR4+ CTCs (n) | CXCR4+ CTCs (%) | CXCR4+ tumour cells on FFPE (%) | Nuclear localisation (%) | Cytoplasmic localisation (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Pancreas | G2 | WD | 6% | Yes | 361 | 141 | 39 | 100 | 100 | 0 |
2 | Midgut | G2 | WD | 15% | Yes | 18 | 6 | 33 | 100 | 40 | 60 |
3 | Midgut | G1 | WD | < 2% | Yes | 8 | 4 | 50 | 90 | 0 | 90 |
4 | Bronchial | G3 | PD | 50% | Yes | 1 | 0 | 0 | 80 | 80 | 0 |
5 | Bronchial | G2 | WD | 10–12% | Yes | 179 | 113 | 63 | 100 | 100 | 0 |
6 | Midgut | G2 | WD | 1–15% | Yes | 2 | 2 | 100 | ND | ND | ND |
7 | Bronchial | G2 | WD | 12% | Yes | 6 | 3 | 50 | 60 | 50 | 10 |
8 | Pancreas | G2 | WD | 5% | Yes | 1 | 1 | 100 | ND | ND | ND |
9 | Midgut | G1 | WD | < 1% | Yes | 23 | 21 | 91 | ND | ND | ND |
10 | Bronchial | G2 | WD | 8% | Yes | 78 | 8 | 10 | 20 | 5 | 15 |
11 | Midgut | G1 | WD | < 1% | Yes | 3 | 2 | 67 | 100 | 100 | 0 |
12 | Pancreas | G3 | WD | 50% | Yes | 70 | 35 | 50 | 100 | 100 | 0 |
13 | Pancreas | G2 | WD | 12% | Yes | 4 | 3 | 75 | 100 | 100 | 0 |
14 | Midgut | G3 | PD | 80% | No | 23 | 7 | 30 | ND | ND | ND |
15 | Pancreas | G2 | WD | 4% | No | 1 | 0 | 0 | 100 | 100 | 0 |
16 | Pancreas | G2 | WD | 15% | No | 4 | 0 | 0 | 80 | 80 | 0 |
17 | Pancreas | G2 | WD | 8% | No | 1 | 1 | 100 | ND | ND | ND |
18 | Pancreas | G2 | WD | 12% | No | 28 | 4 | 14 | 40 | 40 | 0 |
19 | Bronchial | G3 | WD | 25% | No | 40 | 11 | 27 | 40 | 40 | 0 |
20 | Midgut | G1 | WD | < 2% | No | 42 | 30 | 71 | ND | ND | ND |
