Table 5 Concordance rate in cases with lung metastases alone or with excluding lung metastasis alone

From: A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer

Lung met. alone

Tissue-BEAMing

Total

Concordance% [95% CI]

Sensitivity% [95% CI]

Specificity% [95% CI]

MT

WT

Plasma-BEAMing

MT

7

1

8

64.5 [45.4–80.8]

41.2 [18.4–67.1]

92.9 [66.1–99.8]

WT

10

13

23

Total

17

14

31

 

Excluding lung met. alone

Tissue-BEAMing

Total

Concordance% [95% CI]

Sensitivity% [95% CI]

Specificity% [95% CI]

MT

WT

Plasma-BEAMing

MT

103

13

116

89.2 [84.6–92.7]

88.0 [80.7–93.3]

90.2 [83.7–94.7]

WT

14

119

133

Total

117

132

249

 
  1. MT Mutant, WT Wildtype