Table 2 Risk of gastric adenocarcinoma in participants exposed to prediabetes or diabetes compared with normoglycaemic participants, stratified by covariates, expressed as hazard ratio (HR) and 95% confidence interval (CI)

From: Prediabetes and diabetes in relation to risk of gastric adenocarcinoma

Stratified variable

Gastric adenocarcinoma

Crude modela

Multivariable modelb

 

Number

HR (95% CI)

HR (95% CI)

Sex

 Male

  Normoglycemic

82

Reference

Reference

  Prediabetes or diabetes

45

0.81 (0.56–1.17)

0.80 (0.55–1.16)

 Female

  Normoglycemic

50

Reference

Reference

  Prediabetes or diabetes

42

1.24 (0.82–1.88)

1.20 (0.79–1.84)

Age at entry

 ≤49.5

   

  Normoglycemic

25

Reference

Reference

  Prediabetes or diabetes

10

0.83 (0.39–1.77)

0.90 (0.42–1.93)

 >49.5

  Normoglycemic

107

Reference

Reference

  Prediabetes or diabetes

77

1.00 (0.75–1.35)

0.98 (0.73–1.33)

Body mass index

 ≤25.4

  Normoglycemic

68

Reference

Reference

  Prediabetes or diabetes

34

1.05 (0.70–1.60)

1.05 (0.69–1.59)

 >25.4

  Normoglycemic

64

Reference

Reference

  Prediabetes or diabetes

53

0.90 (0.62–1.30)

0.90 (0.63–1.31)

Tobacco smoking status

 Current smoker

  Normoglycemic

39

Reference

Reference

  Prediabetes or diabetes

33

1.22 (0.77–1.95)

1.21 (0.75–1.94)

 Ex-smoker

  Normoglycemic

41

Reference

Reference

  Prediabetes or diabetes

24

0.89 (0.54–1.48)

0.81 (0.48–1.36)

 Non-smoker

  Normoglycemic

50

Reference

Reference

  Prediabetes or diabetes

26

0.78 (0.48–1.26)

0.81 (0.50–1.32)

  1. aAge was used as the time scale
  2. bAdjusted for sex, calendar year, BMI, tobacco smoking status and education level at baseline; age was used as the time scale
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