Table 3 Risk of gastric cardia and non-cardia adenocarcinoma in participants exposed to prediabetes or diabetes and in those exposed to prediabetes compared with normoglycaemic participants, expressed as hazard ratio (HR) and 95% confidence interval (CI)

From: Prediabetes and diabetes in relation to risk of gastric adenocarcinoma

Exposure and outcome

Gastric adenocarcinoma

Crude modela

Multivariable modelb

 

Number

HR (95% CI)

HR (95% CI)

Cardia adenocarcinoma

  Normoglycaemic

43

Reference

Reference

  Prediabetes or diabetes

27

0.96 (0.59–1.56)

0.94 (0.57–1.54)

Non-cardia adenocarcinoma

  Normoglycaemic

89

Reference

Reference

  Prediabetes or diabetes

60

0.98 (0.70–1.36)

0.97 (0.69–1.35)

Cardia adenocarcinoma

  Normoglycaemic

43

Reference

Reference

  Prediabetes

25

1.28 (0.78–2.11)

1.28 (0.78–2.12)

Non-cardia adenocarcinoma

  Normoglycaemic

92

Reference

Reference

  Prediabetes

42

0.97 (0.67–1.40)

0.97 (0.67–1.40)

  1. aAge was used as the time scale
  2. bAdjusted for sex, calendar year, BMI, tobacco smoking status and education level at baseline; age was used as the time scale
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