Table 3 HR (95% CI) of incident kidney cancer according to BMI and WC categories in clinically relevant subgroupsa

From: Obesity, abdominal obesity and subsequent risk of kidney cancer: a cohort study of 23.3 million East Asians

 

BMI (kg/m2)

WC (cm)

 

<25

≥25

P for interaction

<90 in men,<85 in women

≥90 in men, ≥85 in women

P for interaction

Age

  

0.172

  

<0.001

 <65 years

1

1.33 (1.28–1.38)

 

1

1.36 (1.31–1.42)

 

 ≥65 years

1

1.22 (1.15–1.29)

 

1

1.22 (1.15–1.29)

 

Sex

  

0.008

  

<0.001

 Men

1

1.38 (1.33–1.43)

 

1

1.38 (1.33–1.44)

 

 Women

1

1.28 (1.21–1.35)

 

1

1.24 (1.17–1.32)

 

Hypertension

  

0.485

 

0.117

 No

1

1.33 (1.28–1.39)

 

1

1.33 (1.27–1.40)

 

 Yes

1

1.28 (1.23–1.33)

 

1

1.30 (1.25–1.35)

 

Diabetes mellitus

  

0.056

  

0.492

 No

1

1.35 (1.30–1.39)

 

1

1.32 (1.28–1.37)

 

 Yes

1

1.20 (1.12–1.29)

 

1

1.31 (1.22–1.40)

 

Dyslipidemia

  

0.627

  

0.789

 No

1

1.32 (1.27–1.37)

 

1

1.31 (1.26–1.36)

 

 Yes

1

1.29 (1.22–1.36)

 

1

1.32 (1.25–1.40)

 

Chronic kidney disease

  

0.014

  

0.171

 No

1

1.35 (1.31–1.40)

 

1

1.33 (1.28–1.38)

 

 Yes

1

1.16 (1.07–1.26)

 

1

1.29 (1.19–1.41)

 
  1. HR hazard ratio, CI confidence interval, BMI body mass index, WC waist circumference
  2. aHRs (95% CIs) were obtained using multivariable Cox proportional hazard regression analysis after adjusting for age, sex, smoking status, alcohol consumption, physical activity, income, estimated glomerular filtration rate, hypertension, diabetes mellitus
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