Table 1 Prevalence of gastric carcinoma (GC) metastasis during follow-up in patients in different risk groups

From: A panel of DNA methylated markers predicts metastasis of pN0M0 gastric carcinoma: a prospective cohort study

 

GC metastasis rate (%)

OR (95% CI), high vs. low & moderate risk groups

Patients in the low & moderate risk groups

Patients in the high risk group

Univariate analysis

Multivariate analysis

Sex

 

 Male

7/75 (9.3)

13/46 (28.3)

3.83 (1.40–10.49)

5.38 (1.74–16.68)

 Female

3/38 (7.9)

3/14 (21.4)

3.18 (0.56–18.09)

 

Age (yrs)

 

 <60

4/49 (8.2)

13/34 (38.2)

6.96 (2.03–23.94)

9.81 (2.50–38.46)

 ≥60

6/64 (9.4)

3/26 (11.5)

1.26 (0.29–5.47)

 

Location

 

 Non-cardiac

6/82 (7.3)

8/33 (24.2)

4.05 (1.28–12.81)

5.08 (1.51–17.06)

 Cardiac

4/31 (12.9)

8/27 (29.6)

2.84 (0.75–10.81)

 

Different.

 

 Well/ Mod.

3/42 (7.1)

7/20 (35.0)

7.00 (1.58–31.09)

 

 Poor

7/69 (10.1)

8/36 (22.2)

2.53 (0.84–7.67)

 

Vessel embolus

 

 Negative

7/94 (7.4)

12/49 (24.5)

4.03 (1.47–11.05)

4.13 (1.50–11.40)

 Positive

2/18 (11.1)

3/9 (33.3)

6.40 (0.89–45.99)

 

TNM Stage

 

 I

1/34 (2.9)

3/17 (17.6)

7.07 (0.68–73.99)

 

 II

8/65 (12.3)

11/35 (31.4)

3.27 (1.17–9.13)

4.71 (1.55–14.38)

 III

1/14 (7.1)

2/8 (25.0)

4.33 (0.33–57.65)

 

Chemotherapy

 

 No

3/64 (4.7)

7/33 (21.2)

5.47 (1.31–22.84)

5.22 (1.20–22.62)

 Yes

6/46 (13.0)

9/27 (33.3)

3.78 (1.09–13.14)

4.80 (1.30–17.78)

(Total)

10/113 (8.8)

16/60 (26.7)

3.75 (1.58–8.90)

4.71 (1.85–12.00)

  1. Bold values indicate statistical significance p < 0.05