Table 1 Median population density expressed as a percentage of positive cellsa

From: Spatial proximity between T and PD-L1 expressing cells as a prognostic biomarker for oropharyngeal squamous cell carcinoma

Cell type

All

HPV positive

HPV negative

 

T cells

Median percentage of positive cells

P value

CD8+

6.60%

8.90%

4.90%

0.034

CD8+PD-1+

1.50%

1.70%

1.10%

0.111

Macrophages

CD68+

3.10%

6.00%

2.10%

0.035

CD68+PD-L1+

1.10%

2.20%

0.70%

0.058

PD-L1 and PD-1

PD-L1+

9.00%

9.00%

7.40%

0.356

PD-1+

12.70%

13.50%

10.90%

0.284

  1. aPercentage cell expression was first assessed for individual ROIs, and the median expression from all ROI was selected to represent the patient