Table 3 Multivariable model for CB versus NCB, containing clinical and genomic factors.

From: A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma

Variable

Beta ± SE

OR (95% CI)

p-value

Points

c-statistic (95% CI)

Model intercept

1.15 ± 0.97

3.16 (0.47, 21.14)

0.237

1.0

0.90 (0.80, 0.99)

Visceral/LN Mets.

−2.93 ± 1.06

0.05 (0.01, 0.43)

0.006

−2.5

Neut/lymph ratio (≥5 vs. <5)

−2.11 ± 1.14

0.12 (0.01, 1.15)

0.066

−2.0

SNV count (≥10 vs. <10)

3.21 ± 0.97

24.79 (3.73, 164.70)

<0.001

3.0

Back to article page