Fig. 4: Correlation of drug response between patient-derived derivatives. | British Journal of Cancer

Fig. 4: Correlation of drug response between patient-derived derivatives.

From: Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies

Fig. 4

Eight matched PDXCs and PDXs (MM358X1, MM337X1, MM321X1, MM302X, MM313X, MM314X, MM334X and MM325X) were treated with (a) vemurafenib, (b) cobimetinib or (c) vemurafenib + cobimetinib. A Spearman correlation analysis was performed comparing the response in PDXs to the drug score obtained in HTDS.

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