Fig. 4: Patterns of immune augmentation upon neoadjuvant chemotherapy.
From: Baseline immunity and impact of chemotherapy on immune microenvironment in cervical cancer
a Heatmap for the comparison of immune infiltration in paired pre-NACT (n = 43) and post-NACT (n = 43) samples clustered by immune subtypes. b Kaplan–Meier curves of progression-free survival (PFS) for good and poor responders to NACT. All patients who received neoadjuvant chemotherapy and had clinical follow-up information were included in the analysis. P value was based on log-rank test. c Relative levels of immunohistochemical staining intensities in pre- and post-NACT tumour samples of 44 good responders. Blue labels: significant decrease; red labels: significant increase; black labels: statistically unchanged. d Relative levels of immunohistochemical staining intensities in pre- and post-NACT tumour samples of 21 poor responders. Blue labels: significant decrease; red labels: significant increase; black labels: statistically unchanged.
