Fig. 2: Hoxb9 transgenic animals have a larger X zone.
From: HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours
a Dab2, Cyp11b2 and Cyp11b1 immunohistochemistry on sections from wild-type and Hoxb9 t/g male and female adrenal glands. b qRT-PCR of Cyp11b1 and Cyp11b2 on wild-type and Hoxb9 t/g adrenal glands. The data represent the mean ± SD from three biological repeats. c Tyrosine Hydroxylase (TH) and 20α-HSD immunohistochemistry on sections from wild-type and Hoxb9 t/g 3- and 12-month-old female adrenal glands. d qRT-PCR of Akr1c18 and Pik3c2g on female wild-type and Hoxb9 t/g adrenal glands. The data represent the mean ± SD from three biological repeats. m is the medulla, arrows indicate positive cells. Student’s t test, *P < 0.05. Hoxb9 t/g indicates Sf-1:Hoxb9 transgenics.
