Table 1 Patient and clinical characteristics for plasmacytoid urothelial carcinoma and urothelial carcinoma not otherwise specified cohorts.

From: Natural history, response to systemic therapy, and genomic landscape of plasmacytoid urothelial carcinoma

 

All PUC

Up-front surgery PUC

NAC PUC

LA PUC

UC NOS

 

(N = 81)

(N = 29)

(N = 33)

(N = 18)

(N = 146)

Age

 Median (range)

65 (22–84)

50 (43–84)

59 (43–76)

64 (22–84)

65 (39–82)

Sex

 Male

53 (65)

19 (66)

25 (76)

8 (44)

101 (46)

 Female

28 (35)

10 (35)

8 (24)

10 (56)

45 (31)

Clinical T stage

 T2

57 (70)

28 (97)

23 (70)

5 (27.8)

67 (45.9)

 T3–4

24 (30)

1 (3)

10 (30)

13 (72.2)

79 (54.1)

Clinical N stage

 Negative

73 (90)

29 (100)

33 (100)

8 (44.4)

146 (100)

 Positive

8 (10)

0 (0)

0 (0)

10 (55.6)

0 (0)

EUA findings

 Normal

50 (62)

14 (48)

30 (91)

6 (33)

N/A

 LA/invasive

12 (15)

0 (0)

0 (0)

11 (61)

N/A

 ND/NP

19 (24)

15 (52)

3 (9)

1 (6)

N/A

Preoperative chemotherapy

 Yes

51(63)

0 (0)

33 (100)

18 (100)

146 (100)

 No

30 (37)

29 (100)

0 (0)

0 (0)

0 (0)

Platinum type

 Cisplatin based

46 (90)

N/A

33 (100)

13 (72)

146 (100)

 Carboplatin based

5 (10)

N/A

0 (0)

5 (28)

0 (0)

Duration of systemic therapy

 4 cycles

29 (57)

N/A

27 (82)

2 (11)

146 (100)

 >4 cycles

22 (43)

N/A

6 (18)

16 (89)

0 (0)

  1. The patient and clinical characteristics of the patients in the study are shown. Values represent frequency (percentage) unless specified otherwise.
  2. PUC plasmacytoid urothelial carcinoma, NAC neoadjuvant chemotherapy, LA locally advanced, UC NOS urothelial carcinoma not otherwise specified, EUA examination under anaesthesia, N/A not applicable, ND/NP not documented/not performed.