Table 4 Baseline and 5-week mobility and bladder function scores.

From: Non-inferiority randomised phase 3 trial comparing two radiation schedules (single vs. five fractions) in malignant spinal cord compression

  

Baselinea

5-week

Between arms

 

n

Mean

SD

Mean

SD

Differencec

95% CI

p

Mobility score

     

0.24

–0.12 to 0.6b

0.077*/0.038**

  20 Gy/5Fx

37

1.76

0.83

2.05

0.81

  

  10 Gy/SF

36

1.67

0.86

1.72

0.81

  

Bladder function score

     

0.05

−35 to 0.45

0.487*

 20 Gy/5Fx

36

1.54

0.84

1.78

0.96

   

 10 Gy/SF

35

1.34

0.72

1.51

0.89

   
  1. SD standard deviation, CI confidence interval, Gy gray, Fx fractions, SF single fraction.
  2. aHigher score indicates worse mobility or bladder function.
  3. bComparability was defined by the lower bound not exceeding –0.4.
  4. cEstimated difference of 10 Gy/SF minus 20 Gy/5Fx; a positive difference favours SF.
  5. p: significance level resulting from the ANCOVA model, including terms for treatment, and baseline covariate. * Two-sided; ** one-sided.
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