Fig. 1: LPD decomposition of the MSKCC dataset.
From: A novel stratification framework for predicting outcome in patients with prostate cancer
a DESNT bar chart from the LPD decomposition of the MSKCC dataset,14 showing the number ID assigned to 23 example samples that had some amount of DESNT signature. b, c Pie charts showing the relative proportions of the eight LPD signatures in 23 example samples. DESNT is in red; other LPD signatures are represented by different colours as indicated in the key. The number next to each pie chart indicates which cancer it represents from the bar chart above. Individual cancer samples were assigned as a “DESNT cancer” when the DESNT signature was the most abundant; examples are shown in the right-hand box (c, “DESNT”). Many other cancer samples contained a smaller proportion of DESNT cancer: examples shown in a larger box (b, “SOME DESNT”).
