Table 2 Univariate and multivariate cox analysis of RFS in the training cohort (n = 195).

Sex (female vs. male)

1.467

0.874–2.462

0.147

NA

Age, years (≤50 vs. >50)

1.165

0.792–1.713

0.437

NA

HBsAg (negative vs. positive)

1.167

0.686–1.983

0.569

NA

AFP, ng/ml (≤20 vs. >20)

1.248

0.844–1.845

0.267

NA

GGT, U/l (≤54 vs. >54)

1.832

1.255–2.676

0.002

1.652

1.117–2.441

0.012

Liver cirrhosis (no vs. yes)

1.739

1.023–2.956

0.041

1.989

1.156–3.423

0.013

Tumour size, cm (≤5 vs. >5)

1.592

1.086–2.333

0.017

1.420

0.935–2.154

0.100

Microvascular invasion (no vs. yes)

1.640

1.110–2.423

0.013

1.523

0.707–3.277

0.282

Tumour differentiation (I–II vs. III–IV)

1.661

1.104–2.499

0.015

1.509

0.996–2.287

0.052

TNM stage (I vs. II)

1.713

1.133–2.590

0.011

1.107

0.492–2.490

0.805

BCLC stage (0 vs. A)

1.083

0.645–1.818

0.762

NA

HCC-IHC classifier (high vs. low)

1.649

1.133–2.400

0.009

1.593

1.083–2.344

0.018