Table 2 Efficacy Outcomes.

From: Neoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinoma: a Phase 2 study for clinical and biomarker analysis

Outcome

Total (N = 44)

Best response to preoperative mFOLFIRINOX

  Partial response

15 (34.1%)

  Stable disease

28 (63.6%)

  Progressive disease

1 (2.3%)

1-year PFS rate (95% CI)

52.3% (37.6–67.0)

2-year OS rate (95% CI)

50.8% (34.5–67.1)

Median PFS, months (95% CI)

12.2 (8.9–15.5)

Median OS, months (95% CI)

24.7 (12.6–36.9)

Surgery

27 (61.4%)

Median DFS from surgery, months (95% CI) (n = 27)

10.4 (9.2–11.6)

  1. PFS progression-free survival, OS overall survival, DFS disease-free survival.