Fig. 5: Results of flow cytometry of fresh tumour samples in cohort C. | British Journal of Cancer

Fig. 5: Results of flow cytometry of fresh tumour samples in cohort C.

From: Enrichment of the tumour immune microenvironment in patients with desmoplastic colorectal liver metastasis

Fig. 5

a Box and whisker plots of the relative proportion of individual T cell subsets stratified by histopathological growth pattern (HGP). Ratios are displayed on a logarithmic scale. The white line represents the median, the box represents the interquartile range (IQR), and the whisker represents the range. Outliers are defined according to the 1.5 rule (i.e. outside [Q1 − 1.5 × IQR; Q3 + 1.5 × IQR]). b Linear regression models of the relative proportion of individual T cell subsets (y-axis) and the percentage of the desmoplastic-type histopathological growth pattern (dHGP) scored at the tumour–liver interface (x-axis). Ratios are displayed on a logarithmic scale. The blue line represents the regression coefficient; the light blue ribbon represents the corresponding 95% confidence interval. Measurements of individual patients are displayed using dots. Red dots represent patients with non-dHGP (i.e. <100% dHGP), and blue dots represent patients with dHGP (i.e. 100% dHGP).

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