Fig. 5: Survival correlates with IL-10-producing macrophages.
From: The role of sex in the innate and adaptive immune environment of metastatic colorectal cancer
FCA was performed on dissociated tumour, stained for macrophages that were F4/80 + CD11b+. a No difference was observed in total TME macrophage populations. b Females have a higher percentage of macrophages (F4/80 + CD11b+) that are producing IL-10 in the TME. c Mice with above mean macrophages in the TME had no survival benefit, but d mice with above mean IL-10 macrophages survived longer. *p < 0.050, **p < 0.010, ***p < 0.001; n = 6–8.
