Table 2 Characteristics of the breast cancer-free female cohort.

From: Machine learning-based lifetime breast cancer risk reclassification compared with the BOADICEA model: impact on screening recommendations

Demographics and clinical characteristics

Breast cancer-free female cohort, N = 36,146 (% or ± SD)

Age (years)

51.09 ± 15.35

Age at menarche (years)

12.82 ± 1.51

Age at first live birth (nulliparous excluded, years)

24.10 ± 5.03

Parity (nulliparous excluded)

1.92 ± 1.32

Age at menopause (premenopausal women excluded, years)

47.94 ± 6.68

Ashkenazi Jewish ancestry

239 (0.66%)

Ethnicity (Black)

828 (2.29%)

BRCA1 or BRCA2 germline pathogenic variants

115 (462 tested)

Cancer diagnosis (all types)

2 617 (7.24%)

 Age at cancer onset (years)

57.44 ± 15.96

Colorectal cancer

574 (1.59%)

 Age at colorectal cancer onset (years)

61.63 ± 17.19

Lung/bronchus cancer

153 (0.42%)

 Age at lung/bronchus cancer onset (years)

62.01 ± 26.18

Pancreatic cancer

136 (0.38%)

 Age at pancreatic cancer onset (years)

66.85 ± 22.94

Ovarian cancer

508 (1.40%)

 Age at ovarian cancer onset (years)

55.96 ± 22.84

  1. N = 36,146 individuals.