Table 5 Logistic regression results for associations of selected factors with diagnosis of cancer.
Category—factor | Cancer N (%) | No cancer N (%) | Single variable ‘unadjusted' | Multivariable ‘adjusted’** | ||
|---|---|---|---|---|---|---|
Odds ratio (95% CI) | Significance | Odds ratio (95% CI) | Significance | |||
Sex | ||||||
Male | 122 (9.4) | 1 182 (90.6) | 1.00 | 0.027 | 1.00 | 0.172 |
Female | 117 (7.1) | 1 529 (92.9) | 0.74 (0.57–0.97) | 0.77 (0.53–1.12) | ||
Age | ||||||
Per year of age | N/A | 1.04 (1.03–1.06) | <0.001* | 1.05 (1.03–1.07) | <0.001* | |
Previous 1° care consultations | ||||||
<= 3 | 122 (8.9) | 1 253 (91.1) | 1.00 | 0.002 | 1.00 | 0.008 |
> 3 | 6 (2.6) | 229 (97.4) | 0.27 (0.12–0.62) | 0.32 (0.14–0.75) | ||
Duration of symptoms | ||||||
<1 week | 2 (8.0) | 23 (92.0) | 1.00 | 0.038 | – | – |
1–4 weeks | 43 (12.4) | 305 (87.6) | 1.62 (0.37–7.12) | – | ||
5–12 weeks | 44 (8.7) | 463 (91.3) | 1.09 (0.25–4.79) | – | ||
3–6 months | 49 (8.6) | 524 (91.4) | 1.08 (0.25–4.70) | – | ||
>6 months | 30 (6.0) | 466 (94.0) | 0.74 (0.17–3.29) | – | ||
Symptoms (selected) | ||||||
Weight loss | N: 76 (7.8) | 901 (92.2) | 1.05 (0.79–1.39) | 0.76 | – | – |
Y: 152 (8.1) | 1 722 (91.9) | |||||
GP clinical suspicion | N: 113 (6.2) | 1 710 (93.8) | 1.91 (1.45–2.50) | <0.001 | 1.88 (1.20–2.94) | 0.006 |
Y: 115 (11.2) | 913 (88.8) | |||||
Pain | N: 154 (8.0) | 1 771 (92.0) | 1.0 (0.75–1.33) | 0.99 | – | – |
Y: 74 (8.0) | 852 (92) | |||||
Nausea/appetite loss | N: 144 (7.2) | 1 864 (92.8) | 1.43 (1.08–1.90) | 0.012 | 1.18 (0.72–1.95) | 0.51 |
Y: 84 (10.0) | 759 (90.0) | |||||
Fatigue | N: 166 (7.2) | 2 139 (92.8) | 1.65 (1.21–2.25) | 0.001 | 1.29 (0.75–2.20) | 0.36 |
Y: 62 (11.4) | 484 (88.6) | |||||
Anaemia | N: 186 (7.3) | 2 369 (92.7) | 2.11 (1.47–3.02) | <0.001 | 1.16 (0.63–2.13) | 0.64 |
Y: 42 (14.2) | 254 (85.8) | |||||
Change in bowel habit | N: 219 (8.0) | 2 504 (92.0) | 0.86 (0.43–1.72) | 0.68 | – | – |
Y: 9 (7.0) | 119 (93.0) | |||||
General condition | N: 222 (8.1) | 2526 (91.9) | 0.70 (0.31–1.62) | 0.41 | – | – |
Y: 6 (5.8) | 97 (94.2) | |||||
Respiratory problem | N: 220 (7.9) | 2 559 (92.1) | 1.45 (0.69–3.07) | 0.33 | – | – |
Y: 8 (11.1) | 64 (88.9) | |||||
Thrombocytosis | N: 226 (8.0) | 2602 (92.0) | 1.10 (0.25–4.71) | 0.9 | – | – |
Y: 2 (8.7) | 21 (91.3) | |||||
Jaundice | N: 226 (8.0) | 2606 (92.0) | 1.36 (0.31–5.91) | 0.69 | – | – |
Y: 2 (10.5) | 17 (89.5) | |||||
Hypercalcaemia | N: 227 (8.0) | 2616 (92.0) | 1.65 (0.20–13.44) | 0.64 | – | – |
Y: 1 (12.5) | 7 (87.5) | |||||
New onset of diabetes | N: 228 (8.0) | 2620 (92.0) | N/A | N/A | – | – |
Y: 0 (–) | 3 (100.0) | |||||
Number of selected symptoms | ||||||
Per additional selected symptom | N/A | 1.34 (1.20–1.49) | <0.001* | 1.09 (0.83–1.43) | 0.53* | |
