Fig. 1: The relation of CDK5RAP3 and CD44 expression in tumours of GA patients and gastric cell lines. | British Journal of Cancer

Fig. 1: The relation of CDK5RAP3 and CD44 expression in tumours of GA patients and gastric cell lines.

From: RETRACTED ARTICLE: CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer

Fig. 1

a The expression of CDK5RAP3 and CD44 in the same patients by IHC and immunofluorescence. Scale bar 50 μm. b Proportion of tumours with low vs. high staining of CDK5RAP3 and CD44. c Kaplan–Meier survival curve comparing overall survival between patients with low or high CDK5RAP3 expression in gastric cancer patients with low CD44 expression. d Kaplan–Meier survival curve comparing overall survival between patients with low or high CDK5RAP3 expression in gastric cancer patients with high CD44 expression. e Western blot demonstrating levels of CDK5RAP3, CD44, Sox2, Oct4, Nanog and c-Myc in monolayers and spheroids conditions of AGS, KATOIII, NCI-N87 and SNU668. f Photos of monolayers and spheroids conditions of AGS and KATOIII cells following immunofluorescence staining for DAPI (blue), CDK5RAP3 (red) and CD44 (green). Scale bar 20 μm. β-actin was used as a loading control.

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