Fig. 3: M2BPGi treatment enhanced the progression of HCC in vitro and in vivo.

HCC cell lines (PLC/PRF/5) treated with M2BPGi were subjected to a a proliferation assay (n = 6, *p < 0.05) and b invasion assay (n = 5, *p < 0.05). c M2BPGi significantly enhanced the growth of xenografted tumours when compared with controls (PBS) (n = 5, *p = 0.0023). d The Ki-67 labelling index was significantly higher in M2BPGi-treated xenograft tumours than in controls (n = 10, *p < 0.01) (×400 magnification).