Table 3 Oestrogen receptor status among the different DCIS grades and the corresponding recurrence rate.
From: The clinical significance of oestrogen receptor expression in breast ductal carcinoma in situ
DCIS grade | Number of ER-positive cases (n = 475, 74%) | Ten-year overall (DCIS and invasive) recurrence rate in the ER-positive group (n = 47, 10%) | Ten-year invasive recurrence rate (n = 28, 6%) | ER-positive invasive recurrence (n = 22, 5%) | Overall recurrence (DCIS and invasive) rate in the ER-positive group (n = 55, 12%) | Overall invasive recurrence rate (n = 34, 7%) | ER-positive invasive recurrence (n = 25, 5%) |
|---|---|---|---|---|---|---|---|
Low (n = 88, 14%) | 82 (94% of low grade) | Four cases (5% of all low-grade ER-positive cases) | 2 (2%) | 2 (100%) | Five cases (6% of all low-grade ER-positive cases) | 3 (3%) | Two cases with available ER data were all ER-positive (100%) |
Intermediate (n = 165, 26%) | 155 (94% of intermediate grade) | 19 (12% of all intermediate-grade ER-positive cases) | 11 (7%) | Nine cases with available ER data were all ER-positive (100%) | 20 (13% of all intermediate-grade ER- positive cases) | 11 (7%) | Nine cases with available ER data were all ER-positive (100%) |
High (n = 390, 60%) | 238 (61% of high grade) | 24 (10% of all high-grade ER-positive cases) | 15 (6%) | 11/12 cases with available ER data were ER-positive (92%) | 30 (13% of all high-grade ER-positive cases) | 20 (8%) | 14/15 cases with available ER data were ER-positive (93%) |
