Fig. 3: Visualisation of 30 selected altered CpG islands analysis in the Discovery and TCGA-CHOL datasets. | British Journal of Cancer

Fig. 3: Visualisation of 30 selected altered CpG islands analysis in the Discovery and TCGA-CHOL datasets.

From: HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples

Fig. 3: Visualisation of 30 selected altered CpG islands analysis in the Discovery and TCGA-CHOL datasets.The alternative text for this image may have been generated using AI.

a, b Discovery dataset (a) and TCGA-CHOL dataset (b) unsupervised hierarchical clustering analysis based on the average CGI β-values for the 30 BTC-specific altered CGIs. c ROC curves for the 11 CGIs showing an AUC ≥ 0.90 in the Discovery dataset. Red arrows indicate CGIs showing an AUC ≥ 0.90 also in TCGA-CHOL dataset.

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