Table 1 Summarized characteristics of 45 eligible observational studies.
From: A systematic review of microbial markers for risk prediction of colorectal neoplasia
Characteristics | Number of studies (%) |
|---|---|
Participant region | |
Europe | 10 (22.2) |
Asia | 26 (57.8) |
America | 8 (17.8) |
Other | 1 (2.2) |
Study design | |
Prospective study | 20 (44.4) |
Retrospective study | 25 (55.6) |
Outcome | |
Diagnosis | 36 (80.0) |
Metastasis | 5 (11.1) |
Survival | 4 (8.9) |
Reason for colonoscopy | |
Routine screening | 26 (57.8) |
qFIT/gFOBT positive | 5 (11.1) |
Symptoms + Screening | 5 (11.1) |
Patients recruited at hospital | 9 (20.0) |
Antibiotic use prior to sample | |
Not in 1–4 weeks | 7 (15.6) |
Not in 4–24 weeks | 18 (40.0) |
At the time of baseline assessment | 3 (6.7) |
Not mention | 17 (37.7) |
Sample collection | |
Faecal samples | 36 (70.0) |
Tissue samples | 6 (13.3) |
Oral samples | 1 (2.2) |
Blood samples | 2 (4.4) |
Database used for taxonomy assignment | |
RDP | 15 (33.3) |
Silva | 6 (13.3) |
Greengenes | 5 (11.1) |
Other | 5 (11.1) |
Not mention | 14 (31.2) |
