Fig. 1: ILC cell lines are generally minimally invasive. | British Journal of Cancer

Fig. 1: ILC cell lines are generally minimally invasive.

From: VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models

Fig. 1

The ILC cell lines, MDA-MB-330, MDA-MB-134VI, UACC-3133 and IPH926 were plated on the surface of Matrigel-coated transwell invasion chambers in their respective growth media with reduced FBS (5%) and were allowed to migrate towards increased FBS concentrations (20%) for (a) 48h or (b) 7 days. Invading cells were stained with crystal violet, counted from five representative images and plotted with the SEM. We considered MDA-MB-330 as an invasive ILC cell line as they were able to invade within 48 h of plating in an invasion chamber, while all other lines tested were considered minimally invasive (n = 3 biological replicates, each with duplicate technical replicates).

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