Table 3 Statistically significant VOCs in the recurrence of UBC in surveillance on Wilcoxon rank-sum testing.

From: Investigation of urinary volatile organic compounds as novel diagnostic and surveillance biomarkers of bladder cancer

VOC

CAS number

Relative change in recurrence of UBC (fold change)

Wilcoxon rank-sum P value

Wilcoxon rank-sum false discovery rate

Nonanal

124-19-6

Decreased (0.314)

P = 2.18 × 10−5

1.07 × 10−3

2-ethylhexan-1-ol

104-76-7

Decreased (0.424)

P = 6.50 × 10−5

1.24 × 10−3

1,1,4a-trimethyl-4,5,6,7-tetrahydro-3H-naphthalen-2-one

4668-61-5

Decreased (0.332)

P = 1.88 × 10−4

1.84 × 10−3

5-ethyl-3-methyloxolan-2-one

2610-98-2

Increased (1.426)

P = 7.57 × 10−5

1.24 × 10−3

4-methylpent-3-enoic acid

504-85-8

Increased (1.111)

P = 1.01 × 10−3

8.29 × 10−3

Heptan-2-one

110-43-0

Increased (1.560)

P = 1.44 × 10−4

1.77 × 10−3

  1. All VOCs were significant in the cancer versus control comparison (bold).
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