Fig. 1: Effect of 5-ALA on the sensitivity of PCA cells to RT.

a Effect of pre-treatment with 5-ALA (1 mM) for 4 h on sensitivity to ionising radiation (IR) was examined by clonogenic assay in PC-3 and DU-145 cells. b Cell apoptosis analysed by flow cytometry after different treatments. c Colony survival after different treatments including pre-treatment with ROS inhibitor, NAC (500 μM) for 24 h. Dose of IR: 3 Gy. Statistical analysis; by Student’s t-test (mean ± SEM, n = 3).