Fig. 1: ESE3 was overexpressed in PSCs and associated with PDAC fibrosis. | British Journal of Cancer

Fig. 1: ESE3 was overexpressed in PSCs and associated with PDAC fibrosis.

From: ESE3-positive PSCs drive pancreatic cancer fibrosis, chemoresistance and poor prognosis via tumour–stromal IL-1β/NF–κB/ESE3 signalling axis

Fig. 1

a IHC of ESE3 protein expression in PSCs and adjacent normal pancreatic tissues. b IHC and Masson’s trichrome staining in consecutive PDAC tissue sections. c Double immunohistochemical staining and correlation analysis between ESE3 protein expression and extent of stromal fibrosis (α-SMA, stromal marker) in PDAC samples. d Multiplex IF staining of ESE3 (red), α-SMA (green) and cytokeratin (CK-19, an epithelial marker, purple) in PDAC samples. e IF staining of ESE3 and α-SMA expression in hpPSCs and ihPSCs. f Association of ESE3 expression in PSCs with DFS (left) and OS (right) in PDAC.

Back to article page