Table 2 Age-adjusted characteristics of Health Professionals Follow-up Study participants with nonmetastatic PCa, according to extreme categories of first health behaviour scores following diagnosis.
From: Post-diagnostic health behaviour scores in relation to fatal prostate cancer
Sample size: | 2021 PCa Behaviour Score, n = 4968 | 2015 PCa Behaviour Score, n = 4605 | WCRF/AICR Score, n = 5223 | ACS Score, n = 5208 | ||||
|---|---|---|---|---|---|---|---|---|
# Points: | 0–1 | 3 | 0–1 | 5–6 | 0–2.5 | 5.25–7 | 0–1.5 | 5–6 |
n | 423 | 1170 | 173 | 645 | 635 | 609 | 568 | 705 |
Mean age at diagnosis, years ± SD | 69 ± 6.7 | 70 ± 7.0 | 69 ± 6.7 | 69 ± 6.8 | 69 ± 7.4 | 70 ± 6.7 | 70 ± 6.7 | 69 ± 6.8 |
Age at diagnosis, % | ||||||||
<65 | 30 | 23 | 25 | 28 | 26 | 22 | 23 | 26 |
65–69 | 28 | 26 | 35 | 26 | 28 | 29 | 30 | 26 |
70–74 | 22 | 26 | 24 | 27 | 23 | 27 | 26 | 27 |
75–79 | 15 | 18 | 13 | 14 | 15 | 16 | 15 | 15 |
≥80 | 5.2 | 6.8 | 2.9 | 5.0 | 7.4 | 6.2 | 6.0 | 5.3 |
Stage at diagnosis, % | ||||||||
T1/N0/M0 | 57 | 61 | 58 | 66 | 65 | 57 | 62 | 63 |
T2/N0/M0 | 42 | 37 | 41 | 31 | 34 | 40 | 36 | 35 |
T3a/N0/M0 | 1.4 | 1.9 | 1.7 | 2.4 | 1.5 | 2.4 | 2.1 | 2.0 |
Gleason score at diagnosisa, % | ||||||||
<7 | 55 | 60 | 60 | 59 | 62 | 59 | 58 | 58 |
7 | 31 | 30 | 26 | 31 | 26 | 31 | 29 | 32 |
>7 | 14 | 9.6 | 15 | 9.9 | 11 | 11 | 12 | 10 |
Median PSA at diagnosisa, ng/mL (IQR) | 7.0 (4.7, 11) | 6.6 (4.8, 10) | 7.0 (4.9, 10) | 6.0 (4.6, 9.2) | 6.5 (4.7, 9.8) | 6.4 (4.6, 9.7) | 7.0 (4.9, 10) | 6.3 (4.7, 9.1) |
PSA at diagnosisa, % | ||||||||
≤6 | 40 | 43 | 40 | 50 | 46 | 46 | 40 | 46 |
>6–10 | 31 | 32 | 37 | 28 | 31 | 32 | 34 | 33 |
>10–20 | 18 | 19 | 11 | 16 | 16 | 17 | 18 | 15 |
>20 | 11 | 5.7 | 12 | 6.2 | 7.4 | 6.2 | 8.3 | 5.5 |
Primary treatmenta, % | ||||||||
Radical prostatectomy | 40 | 52 | 43 | 43 | 43 | 48 | 43 | 50 |
Radiation | 40 | 34 | 43 | 42 | 42 | 35 | 43 | 36 |
Hormone therapy | 9.8 | 4.1 | 7.3 | 3.3 | 4.8 | 6.0 | 6.0 | 3.6 |
Watchful waiting | 7.1 | 8.1 | 3.8 | 9.9 | 7.5 | 8.9 | 6.2 | 8.7 |
Other | 3.3 | 1.6 | 2.5 | 1.6 | 2.4 | 1.7 | 1.7 | 1.4 |
Year of diagnosis, % | ||||||||
1994 or earlier | 23 | 23 | 25 | 17 | 16 | 25 | 18 | 17 |
1995–1999 | 22 | 21 | 18 | 21 | 24 | 20 | 23 | 21 |
2000–2004 | 27 | 23 | 29 | 26 | 28 | 25 | 30 | 23 |
2005–2009 | 21 | 24 | 20 | 25 | 24 | 19 | 20 | 26 |
2010 or later | 7.5 | 9.3 | 6.8 | 11 | 7.8 | 12 | 8.4 | 13 |
Non-Hispanic White, % | 95 | 97 | 95 | 97 | 96 | 95 | 97 | 97 |
Family history of PCa, % | 11 | 18 | 18 | 17 | 15 | 17 | 14 | 17 |