Fig. 4: Table of parameter estimates.
Bootstrapped distributions for the variables (a) nGFX, b rLOH, c nTSX (see the section “LOH in malignant schwannoma”), and (d) u. These were determined by the frequency of LOH from [11], by our own attempted measurements of pathological SMARCB1 variants, and by incidence data from ref. [1]. Equations (13), (14) and (18) allowed estimates of nGFX, rLOH and u to be generated. The box represents the median estimate and inter-quartile range; the outer whiskers represent the 2.5% and 97.5% quantiles, i.e., the 95% confidence interval [48]. Note that the distributions for nGFX and nTSX appear to be bimodal.
