Fig. 7: Relative frequency pLOH of LOH in Schwann cells and colonic crypt cells.

a Quantiles for bootstrapped distributions for pLOH estimates (above). b Visualisations of the distributions for Schwann progenitor cells, and (c) colorectal crypt progenitor cells, demonstrating a substantial difference in order of magnitude. The estimates for colon cells were derived from Huang et al. [74] and Paterson et al. [13]. The estimates for Schwann cells are original to this work.