Table 1 SIR and AER for development of specific subsequent primary oral cancers among all 5-years cancer survivors in the PanCareSurFup cohort (N = 64,460).

From: Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study

Type of SPN

Median age

Obs (%)

Exp

SIR (95% CI)

AER (95% CI)

Salivary gland

27.8

64 (44%)

3.7

17.2 (14.4–20.4)

4.8 (4.0–5.7)

Tongue

32.4

38 (26%)

6.4

5.9 (4.7–7.4)

2.5 (1.9–3.3)

Other oral cavity

35.3

21 (14%)

5.7

3.7 (2.7–5.0)

1.2 (0.8–1.8)

Pharynx

44.7

20 (14%)

9.4

2.1 (1.6–2.9)

0.8 (0.5–1.5)

Lip

23.0

2 (1.4%)

1.5

1.4 (0.5–3.6)

0.0 (0.0–1.7)

Overall

32.4

145 (100%)

29.2

5.0 (4.4–5.6)

9.2 (7.9–10.6)

  1. SPN subsequent primary malignant neoplasm, Obs observed, Exp expected, SIR standardised incidence ratio, CI confidence interval, AER absolute excess risks.
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