Fig. 3: Immunohistochemical analyses reveal a mixture of cell surface and cytoplasmic FRα protein expression in ovarian cancer tissues. | British Journal of Cancer

Fig. 3: Immunohistochemical analyses reveal a mixture of cell surface and cytoplasmic FRα protein expression in ovarian cancer tissues.

From: Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Fig. 3: Immunohistochemical analyses reveal a mixture of cell surface and cytoplasmic FRα protein expression in ovarian cancer tissues.

a Percentage of patients with tumours expressing FRα on the membrane, in the cytoplasm, both or neither, and with membrane staining on 0–<5, 5–<25, 25–<50 or ≥50% of tumour cells. b Top left: Overall percentage of patients with each tumour histotype; Top right: Percentage of patients with membrane and cytoplasmic positivity within each histotype subgroup; Bottom left: Percentage of patients within each histotype subgroup with different proportions of membrane positive tumours cells; Bottom right: Immunohistochemical H scores calculated in each histotype subgroup.

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