Table 2 a. The relationship between serum LDH, weight loss and 3-month survival in patients with advanced cancer (n = 421). b. The relationship between serum LDH, low BMI and 3-month survival in patients with advanced cancer (n = 436). c. The relationship between serum LDH, low skeletal muscle mass and 3-month survival in patients with advanced cancer (n = 177). d. The relationship between serum LDH, disease burden and 3-month survival in patients with advanced cancer (n = 436). e. The relationship between serum LDH, NLR and 3-month survival in patients with advanced cancer (n = 436). f. The relationship between serum LDH, mGPS and 3-month survival in patients with advanced cancer (n = 436).

From: Lactate dehydrogenase: relationship with the diagnostic GLIM criterion for cachexia in patients with advanced cancer

a

 

LDH < 250 Units/L (n = 107)

LDH 250–500 Units/L (n = 173)

LDH > 500 Units/L (n = 141)

P valuea

Weight loss ≤ 5% (n = 282)

63 (57%)

92 (51%)

51 (35%)

<0.001

Weight loss > 5% (n = 139)

28 (25%)

26 (14%)

18 (12%)

  0.002

P valuea

0.048

<0.001

0.146

 

b

 

LDH ≤ 250 Units/L (n = 110)

LDH 250–500 Units/L (n = 180)

LDH > 500 Units/L (n = 146)

P valuea

Normal/high BMI (n = 293)

78 (73%)

82 (47%)

54 (38%)

<0.001

Low BMI (n = 143)

17 (16%)

39 (23%)

16 (11%)

  0.008

P valuea

0.002

0.005

0.031

 

c

 

LDH ≤ 250 Units/L (n = 66)

LDH 250–500 Units/L (n = 54)

LDH > 500 Units/L (n = 57)

P valuea

Normal/high SMI (n = 80)

31 (47%)

18 (33%)

14 (25%)

  0.006

Low SMI (n = 97)

28 (42%)

22 (41%)

17 (30%)

  0.001

P valuea

0.230

0.747

0.266

 

d

 

LDH ≤ 250 Units/L (n = 110)

LDH 250–500 Units/L (n = 180)

LDH > 500 Units/L (n = 146)

P valuea

Non-metastatic disease (n = 81)

17 (15%)

31 (17%)

9 (6%)

  0.035

Metastatic disease (n = 355)

76 (69%)

90 (50%)

61 (42%)

<0.001

P valuea

0.950

0.599

0.661

 

e

 

LDH < 250 Units/L (n = 110)

LDH 250–500 Units/L (n = 180)

LDH > 500 Units/L (n = 146)

P valuea

NLR < 3 (n = 151)

41 (37%)

57 (32%)

31 (21%)

  0.001

NLR 3–5 (n = 92)

28 (25%)

25 (14%)

14 (10%)

  0.057

NLR > 5 (n = 193)

24 (22%)

39 (22%)

25 (17%)

<0.001

P valuea

0.001

<0.001

<0.001

 

f

 

LDH < 250 Units/L (n = 110)

LDH 250–500 Units/L (n = 180)

LDH > 500 Units/L (n = 146)

P valuea

mGPS 0 (n = 166)

49 (45%)

67 (37%)

30 (21%)

  0.002

mGPS 1 (n = 90)

12 (11%)

25 (14%)

17 (12%)

  0.005

mGPS 2 (n = 180)

32 (29%)

29 (16%)

23 (16%)

<0.001

P valuea

<0.001

<0.001

<0.001

 
  1. Each cell (n = /%).
  2. ap value is from χ2 analysis.
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