Table 1 Summary of mouse models used in this study.
From: MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer
Model name | Genotype of mouse model | |
|---|---|---|
Small cohort (n = 18) | AP | villinCreER Apcfl/+ Trp53fl/fl (n = 3) |
APN | villinCreER Apcfl/+ Trp53fl/fl Notch1Tg/+ (n = 3) | |
KP | villinCreER KrasG12D/+ Trp53fl/fl (n = 3) | |
KPN | villinCreER KrasG12D/+ Trp53fl/fl Notch1Tg/+ (n = 9) | |
Large cohort (n = 39) | A | villinCreER Apcfl/+ (n = 6) |
AK | villinCreER Apcfl/+ KrasG12D/+ (n = 6) | |
BP | villinCreER BrafV600E/+ Trp53fl/fl (n = 4) | |
BPN | villinCreER BrafV600E/+ Trp53fl/fl Notch1Tg/+ (n = 7) | |
KP | villinCreER KrasG12D/+ Trp53fl/fl (n = 6) | |
KPN | villinCreER KrasG12D/+ Trp53fl/fl Notch1Tg/+ (n = 10) |
