Fig. 5: Difference in chromatin accessibility between CA-C and other tumours. | British Journal of Cancer

Fig. 5: Difference in chromatin accessibility between CA-C and other tumours.

From: Chromatin profile-based identification of a novel ER-positive breast cancer subgroup with reduced ER-responsive element accessibility

Fig. 5

a Volcano plot showing the differential accessibility analysis of CREs between CA-C and CA-A tumours. Significantly different CREs are coloured according to the clusters corresponding to Fig. 4b. b, c Bar plots of the motif enrichment significance (P-value) of Homer known motifs for CA-A–specific peaks (b) and CA-C–specific peaks (c). Known motif sequences are shown on the right. d Volcano plot showing the differential accessibility analysis of CREs between CA-C and CA-B tumours. Significantly different CREs are coloured according to the clusters corresponding to Fig. 4b. e, f Bar plots of the motif enrichment significance (P-value) of Homer known motifs for CA-B–specific peaks (e) and CA-C–specific peaks (f). Known motif sequences are shown on the right.

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