Fig. 2: Dectin-1 is predominantly expressed on macrophages in GC. | British Journal of Cancer

Fig. 2: Dectin-1 is predominantly expressed on macrophages in GC.

From: C-type lectin receptor Dectin-1 blockade on tumour-associated macrophages improves anti-PD-1 efficacy in gastric cancer

Fig. 2

a Representative flow cytometric histograms showing the expression of Dectin-1 on gated tumour-infiltrating immune cell subsets in tumour tissues of GC. b Quantitative data on cellular composition of total CD45+ immune cells (left) and CD45+Dectin-1+ cells (right), including B cells (CD3−CD19+), T cells (CD3+CD19−), NK cells (CD3−CD56+), macrophages (CD68+) and DCs (HLA-DR+CD11c+) (n = 27). c The percentage of B cells, T cells, NK cells, macrophages and DCs among Dectin-1+ cells in tumour tissues and corresponding peritumor tissues of GC (n = 15). Paired t test. d Representative immunofluorescence staining of Dectin-1 (red), CD68 (green) and DAPI (blue) in tumour tissues of GC (scale bar, 100 μm). Dectin-1+ TAMs are circled with white frame (scale bar of the magnified image, 50 μm). **P < 0.01.

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