Fig. 4: Direct cytotoxicity and ADCC by pCR status. | British Journal of Cancer

Fig. 4: Direct cytotoxicity and ADCC by pCR status.

From: Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy

Fig. 4: Direct cytotoxicity and ADCC by pCR status.The alternative text for this image may have been generated using AI.

Paired pre- and post-treatment direct cytotoxicity levels of patient PBMCs against a K562 and b SKBR3 by pCR. The K562 dataset lost a paired pCR sample due to a technical issue acquiring the sample. c Pre- and post-treatment trastuzumab-mediated ADCC against SKBR3 by patient PBMCs by pCR. A paired Student’s t test was used to determine statistical significance. All p values were adjusted for multiple testing. NS not significant.

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