Table 1 Clinicopathological information of 56 HCC patients analyzed in the present study.

Case

36

20

Age (median ± SD)

72.5 ± 9.6

72 ± 14.0

n.s.^a

Sex (male/female)

24/12

18/2

p = 0.06^b

Body mass index (kg/m²)

22.6 ± 3.0

22.6 ± 4.8

n.s.^a

Performance status (PS0/1/2)

31/5/0

17/1/1

Etiology

(HBV/HCV/HBV + HCV/Alcohol/ NASH/PBC + AIH/unknown)

13/7/4/3/3/2/4

4/3/2/6/3/1/1

Total bilirubin (mg/dL)

0.8 ± 0.4

0.6 ± 0.3

n.s.^a

AFP (ng/mL)

9.8 ± 214885.9

193 ± 234358.5

p = 0.026^a

DCP (mAU/mL)

316.5 ± 11634.9

405 ± 31599.4

n.s.^a

Inflammation

(A0/1/2/3/unknown)

4/8/3/0/21

1/1/2/0/16

Fibrosis (F0-1/2/3-4)

11/16/8

5/7/8

n.s.^b,c

Tumor size

4.3 ± 4.2

4.1 ± 13.3

n.s.^a

BCLC stage (A/B/C)

16/16/4

11/6/3

Tumor classification

(Simple nodular/Contiguous multinodular/Others)

24/8/2

12/6/2

Differentiation

(Well/Moderately/Poorly)

3/28/5

0/9/11

p = 0.002^b,d

Pathological structure

(Microtrabecular/Macrotrabecular/Compact/Pseudoglandular/Schirrhous/Unclassified)

20/3/5/4/2/2

2/7/8/1/0/2

p = 0.025^b,e