Fig. 5: FSCN1 loss affects prostate cancer cell growth in vitro and in vivo. | British Journal of Cancer

Fig. 5: FSCN1 loss affects prostate cancer cell growth in vitro and in vivo.

From: Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor

Fig. 5

a FSCN1 protein expression was assessed by western blotting in PC3M cells expressing shScramble, shFSCN1.2, and shFSCN1.3, respectively. GAPDH was used as a loading control. b Cell proliferation of PCM3 cells expressing shScramble, shFSCN1.2, and shFSCN1.3 was assessed by MTT assay. c Cell migration of PCM3 cells expressing shScramble, shFSCN1.2, and shFSCN1.3 was assessed by Transwell assay. Relative cell numbers of cells per field are shown. d PC3M cells expressing shScramble, shFSCN1.2, or shFSCN1.3 were implanted subcutaneously, and tumour growth was assessed by biweekly measurements. e Tumour weight of PC3M tumours expressing shScramble, shFSCN1.2, or shFSCN1.3 at the endpoint. f Images of excised tumours at the endpoint.

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